Issn  2249-7579
e Issn  2249-7579
Publisher JOURNAL OF PHARMACEUTICAL BIOLOGY
Title

IMMUNOMODULATORY ACTIVITY OF TINOSPORA SINENSIS

Authors
G. Sandhyarani
Vaageswari College of Pharmacy, Karimnager, Andhra Pradesh, India
K. Praveen Kumar
Vaagdevi College of Pharmacy, Medicinal Chemistry Research Division, Hanamkonda, Warangal, Andhra Pradesh, India
Keywords
Tinospora sinensis Dunal ,Immunomodulation ,Haemagglutination titre (HT) ,Delayed type of hypersensitivity (DTH) response ,

Abstract

The present study was undertaken to evaluate the effect of some selected medicinal plants on immunomodulatory activity that comprises of screening to identify the activity of ethanolic extract of medicinal plants on humoral and cell mediated immunity (specific immune response). Experiments were conducted in vivo in Swiss albino mice. Tinospora sinensis ethanolic extract was found to enhance humoral immune response on 7th day by 12 % as compared to the standard control cyclophosphamide that exhibited 54% humoral immune response, whereas cell mediated immune response was observed with an enhancement in the values (19.27%) in comparison with controlcyclosporine (37.63%).

Volume / Issue / Year

4 , 1 , 2014

Starting Page No / Endling Page No

61 - 63