A REVIEW ON ORAL CONTROL DRUG DELEVERY SYSTEM
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati, Andhra Pradesh- 517 561, India
Subhashis Debnath
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati, Andhra Pradesh- 517 561, India
M. Niranjan Babu
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati, Andhra Pradesh- 517 561, India
ACT Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. These routes provide promising alternatives to parenteral drug delivery particularly for peptide and protein therapeutics. For this purpose, several drug delivery systems have been formulated and are being investigated for nasal and pulmonary delivery. These include liposomes, proliposomes, microspheres, gels, prodrugs, cyclodextrins, among others. Nanoparticles composed of biodegradable polymers show assurance in fulfilling the stringent requirements placed on these delivery systems, such as ability to be transferred into an aerosol, stability against forces generated during aerosolization, biocompatibility, targeting of specific sites or cell populations in the lung, release of the drug in a predetermined manner, and degradation within an acceptable period of time
3 , 2 , 2013
89 - 93
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