IN-VITRO ANTI BACTERIAL AND EX VIVO CYTOTOXICITY STUDIES OF AERIAL PARTS OF CYPERUS IRIA L
Department of Pharmacognosy, Nirmala College of Health Science, Chalakudy, Thrissur
Sarath lal P.S
Department of Pharmacognosy, Malik Deenar College of Pharmacy, Seethangoli, Bela post, Kasaragod
Ajith Babu T K
Department of Pharmacognosy, Malik Deenar College of Pharmacy, Seethangoli, Bela post, Kasaragod
Poornima M
Department of Pharmacognosy, Malik Deenar College of Pharmacy, Seethangoli, Bela post, Kasaragod
Dias Dileep E
Department of Pharmacognosy, Malik Deenar College of Pharmacy, Seethangoli, Bela post, Kasaragod
Cyperus is the second largest genus of the sedges or cyperaceae family. Cyperus iria (also known as Rice Flat Sedge) is a smooth, tufted sedge found worldwide. It’s an important and widespread weed in south and southeast Asia. The plant is astringent, stimulant, stomachic and tonic. It is used to treat amenorrhoea. The whole plant is used to treat rheumatism and to regulate menstruation. The rhizome is used as a diuretic. A decoction of the ground tubers is used for treating fevers. The objective of present study is pharmacognostical, phytochemical and pharmacological (invitro antimicrobial & exvivo cytotoxicity) studies on aerial parts of Cyperus iria. The extracts of Cyperus Iria.L showed the presence of alkaloids, phenols, steroids, glycosides, flavonoids, terpenoids, carbohydrates and saponins. The extracts obtained were utilized for ex-vivo cytotoxicity studies by Daltons Lymphoma Ascites method. The chloroform extract found to have significant cytotoxicity in mice carcinoma cells. Antimicrobial activity by Disc Diffusion method was performed against both gram positive and gramnegative organisms. The methanolic extract shows significant antimicrobial properties. The phytochemical studies gave conformation of the above said results. The pharmacological studies gave supportive results to affirm the above said activities
12 , 2 , 2020
32 - 39
Subscriber Login
