EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY OF Soymida febrifuga A. Juss
Shree Babasaheb Gharfalkar College of Pharmacy, Gadge Nagar, Nachangaon Road, Pulgaon - 442302, Maharashtra, India
Rupali H. Tiple
Shree Babasaheb Gharfalkar College of Pharmacy, Gadge Nagar, Nachangaon Road, Pulgaon - 442302, Maharashtra, India
Kishor H. Lohiya
Shree Babasaheb Gharfalkar College of Pharmacy, Gadge Nagar, Nachangaon Road, Pulgaon - 442302, Maharashtra, India
Prajakta N. Dongare
Shree Babasaheb Gharfalkar College of Pharmacy, Gadge Nagar, Nachangaon Road, Pulgaon - 442302, Maharashtra, India
Vaishali P. Wasnik
Shree Babasaheb Gharfalkar College of Pharmacy, Gadge Nagar, Nachangaon Road, Pulgaon - 442302, Maharashtra, India
Antioxidant activity of methanolic, water and total aqueous extract of Soymida febrifuga leaves was studied for its free radical scavenging property on different in vitro models e. g. - 1, 1-diphenyl-2-picryl hydrazyl (DPPH) method, nitric oxide method and reducing power method. The extracts showed good dose dependant free radical scavenging property in all the models. IC50 values for methanolic, water and total aqueous extract were found to be 20.56, 70.22 and 36.09 ïg/ml in DPPH method and 77.02 and 70.20 2g/mL in nitric oxide method. In reducing power method, methanolic extract shows more reducing power as compared to water and total aqueous extract. Ascorbic acid was used as standard. It is concluded that the aqueous extract shows more antioxidant activity as compared to methanolic extract.
7 , 2 , 2017
50 - 54
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