FORMULATION AND EVALUATION OF ORAL DISPERSIBLE TABLETS OF ANTI HYPERTENSIVE DRUG ATENOLOL
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati 517561, Andhra Pradesh, India
Shahid Mohammad S
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati 517561, Andhra Pradesh, India
Niranjan Babu M
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati 517561, Andhra Pradesh, India
Oral dispersible tablets has number of advantages viz., faster onset of action, ease of administration, ease of manufacturing, ease of storage and transport. A novel attempt has been made to develop oral dispersible tablets of atenolol by including different ratios of crospovidone, croscarmellose sodium and sodium starch glycolate as super disintegrants. The tablets were prepared by direct compression method. The formulated tablets were evaluated for Pre-formulation and post formulation parameters and they were found to be satisfactory. The formulated oral dispersible tablets possess good drug releasing property, good mouth feel and improved drug bioavailability with better patient compliance
3 , 2 , 2013
79 - 84
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