A REVIEW ON ULTRASONIC MICROBUBBLES
Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra Pradesh – 517102, India
P. Pavani Venkata
Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra Pradesh – 517102, India
C.K. Ashok Kumar
Sree Vidyanikethan College of Pharmacy, Tirupati, Andhra Pradesh – 517102, India
Ultrasound imaging technique is widely using technique. The diagnostic applications of ultrasound imaging have been enormously popular because ultrasound is non-invasive, safest, fastest and less expensive method of scanning for many types of medical diagnosis. Compared with techniques such as magnetic resonance imaging, however image quality is often inferior, and methods for improving image contrast are highly desirable. This review concluded, the application of microbubbles with ultrasound is a widely dispersed technology for medical imaging and for drug/ DNA delivery. Various new microbubble contrast agents present a new era of ultrasound for future application in diagnosis. Microbubbles having conjugated antibodies or binding ligands on their surface are suitable for target drug delivery in cancer therapy and gene delivery. An alteration in chemical composition of microbubbles is required to permit prolonged circulation of them and to prevent their nonspecific removal from the blood pool by the reticulo endothelial system
1 , 1 , 2011
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